Thursday, March 22, 2012

Lipodystrophy Medications


Definition of Lipodystrophy:

Lipodystrophy is a condition characterized by abnormal or degenerative conditions of the body's adipose tissue.

Drugs associated with Lipodystrophy

The following drugs and medications are in some way related to, or used in the treatment of Lipodystrophy. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.





Drug List:

Wednesday, March 21, 2012

Uta


Generic Name: hyoscyamine, methenamine, methylene blue, and phenyl salicylate (HYE oh SYE a meen, meth EN a meen, METH il een BLUE, FEEN il sa LIS il ate)

Brand Names: Darpaz, Hyophen, Phosenamine, Phosphasal, Prosed/DS, Urelle, Uribel, Uro Blue, Ustell, Uta, UTICAP, Utira, Utira-C


What is Uta (hyoscyamine, methenamine, methylene blue, and phenyl salicylate)?

Hyoscyamine produces many effects in the body, including relief from muscle spasms.


Methenamine and methylene blue work as mild antiseptics that fight bacteria in the urine and bladder.


Phenyl salicylate is a mild pain reliever.


The combination of hyoscyamine, methenamine, methylene blue, and phenyl salicylate is used to treat bladder irritation (pain, burning, inflammation) caused by urinary tract infection. This medication is also used to prevent bladder discomfort during a medical procedure.


Hyoscyamine, methenamine, methylene blue, and phenyl salicylate may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Uta (hyoscyamine, methenamine, methylene blue, and phenyl salicylate)?


You should not use hyoscyamine, methenamine, methylene blue, and phenyl salicylate if you are allergic to it.

Before taking this medication, tell your doctor if you have any type of heart problem (congestive heart failure, coronary heart disease, a heart valve or heart rhythm disorder), glaucoma, an enlarged prostate, bladder obstruction, myasthenia gravis, a stomach ulcer or obstruction, or if you are allergic to belladonna (Donnatal and others).


Drink plenty of liquids while you are taking this medication. If you have an eye exam and your pupils are dilated with eye drops, tell the eye doctor ahead of time that you are using hyoscyamine, methenamine, methylene blue, and phenyl salicylate.

Many drugs can interact with this medicine. Also, hyoscyamine can make it harder for your body to absorb other medications you take by mouth. Tell your doctor about all other medicines you use.


What should I discuss with my healthcare provider before taking Uta (hyoscyamine, methenamine, methylene blue, and phenyl salicylate)?


You should not use hyoscyamine, methenamine, methylene blue, and phenyl salicylate if you are allergic to it.

To make sure you can safely take this medication, tell your doctor if you have any of these other conditions:



  • heart disease;




  • a heart rhythm disorder;




  • congestive heart failure;




  • coronary heart disease;




  • a heart valve disorder;




  • glaucoma;




  • an enlarged prostate or bladder obstruction;




  • myasthenia gravis;




  • an ulcer or obstruction in your stomach; or




  • if you are allergic to belladonna (Donnatal and others).




FDA pregnancy category C. It is not known whether this medication will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Hyoscyamine, methenamine, methylene blue, and phenyl salicylate can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Hyoscyamine, methenamine, methylene blue, and phenyl salicylate should not be given to a child younger than 7 years old. Older adults may be more likely to have side effects from this medication.

How should I take Uta (hyoscyamine, methenamine, methylene blue, and phenyl salicylate)?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


Hyoscyamine, methenamine, methylene blue, and phenyl salicylate is usually taken 4 times daily. Follow your doctor's instructions.


Do not crush, chew, or break an enteric coated pill. Swallow it whole. The enteric coated pill has a special coating to protect your stomach. Breaking the pill will damage this coating. Drink plenty of liquids while you are taking this medication. If you have an eye exam and your pupils are dilated with eye drops, tell the eye doctor ahead of time that you are using hyoscyamine, methenamine, methylene blue, and phenyl salicylate. Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe dizziness or rapid pulse.


What should I avoid while taking Uta (hyoscyamine, methenamine, methylene blue, and phenyl salicylate)?


Avoid taking an antacid or anti-diarrhea medicine within 1 hour before or after you take hyoscyamine, methenamine, methylene blue, and phenyl salicylate. Antacids or anti-diarrhea medicine can make it harder for your body to absorb hyoscyamine.


If you also take ketoconazole (Nizoral), wait at least 2 hours after taking it before you take hyoscyamine, methenamine, methylene blue, and phenyl salicylate.


Uta (hyoscyamine, methenamine, methylene blue, and phenyl salicylate) side effects


Methylene blue will most likely cause your urine or stools to appear blue or green in color. This is a normal side effect of the medication and will not cause any harm.


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • severe dizziness, blurred vision, fast heart rate;




  • agitation, confusion, feeling restless or excited;




  • painful or difficult urination; or




  • feeling short of breath.



Less serious side effects may include:



  • mild dizziness;




  • drowsiness; or




  • flushing (warmth, redness, or tingly feeling).



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Uta (hyoscyamine, methenamine, methylene blue, and phenyl salicylate)?


Many drugs can interact with this medicine. Also, hyoscyamine can make it harder for your body to absorb other medications you take by mouth. Tell your doctor about all other medicines you use, especially:



  • atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm Scop);




  • a diuretic (water pill);




  • bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);




  • glycopyrrolate (Robinul);




  • homatropine (Hycodan, Tussigon);




  • methantheline;




  • neostigmine (Prostigmin) or pyridostigmine (Mestinon);




  • bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); or




  • an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);




  • medicines to treat symptoms of Alzheimer's disease such as donepezil (Aricept), galantamine (Razadyne), memantine (Namenda), rivastigmine (Exelon), or tacrine (Cognex);




  • narcotic pain medication such as codeine (Tylenol #3, Cheratuss, Guaiatuss), fentanyl (Actiq, Duragesic), hydrocodone (Lortab, Vicodin, Vicoprofen), hydromorphone (Dilaudid), methadone (Dolophine, Methadose), morphine (Avinza, Kadian, MS Contin, Oramorph), oxycodone (OxyContin, Endocet, Percocet), propoxyphene (Darvocet, Propacet), and others;




  • sodium bicarbonate, potassium citrate (K-Lyte, Urocit-K), sodium citrate and citric acid (Bicitra, Oracit), or sodium citrate and potassium (Citrolith, Polycitra);




  • sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, and others); or




  • ulcer or irritable bowel medications such as dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Hyomax), mepenzolate (Cantil), or propantheline (Pro Banthine).



This list is not complete and there are many other drugs that can interact with hyoscyamine, methenamine, methylene blue, and phenyl salicylate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.



More Uta resources


  • Uta Side Effects (in more detail)
  • Uta Use in Pregnancy & Breastfeeding
  • Uta Drug Interactions
  • 3 Reviews for Uta - Add your own review/rating


  • Uta MedFacts Consumer Leaflet (Wolters Kluwer)

  • Darcalma Prescribing Information (FDA)

  • Darpaz Prescribing Information (FDA)

  • Phosenamine Prescribing Information (FDA)

  • Phosphasal Advanced Consumer (Micromedex) - Includes Dosage Information

  • Phosphasal Prescribing Information (FDA)

  • Prosed EC Advanced Consumer (Micromedex) - Includes Dosage Information

  • Prosed/DS MedFacts Consumer Leaflet (Wolters Kluwer)

  • Urelle Prescribing Information (FDA)

  • Uribel Prescribing Information (FDA)

  • Urimax Delayed-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Urised MedFacts Consumer Leaflet (Wolters Kluwer)

  • Uritact-EC Delayed-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Ustell Prescribing Information (FDA)



Compare Uta with other medications


  • Urinary Tract Infection


Where can I get more information?


  • Your pharmacist can provide more information about hyoscyamine, methenamine, methylene blue, and phenyl salicylate.

See also: Uta side effects (in more detail)


Sunday, March 18, 2012

Simvastatin 80mg Tablets






Simvastatin 80mg Tablets



Read all of this leaflet carefully before you start taking this medicine



  • Keep this leaflet. You may need to read it again


  • If you have any further questions, ask your doctor or pharmacist


  • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours


  • If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.



In this leaflet:


  • 1. What Simvastatin 80mg is and what it is used for

  • 2. Before you take Simvastatin 80mg

  • 3. How to take Simvastatin 80mg

  • 4. Possible side effects

  • 5. How to store Simvastatin 80mg

  • 6. Further information




What Simvastatin 80Mg Is And What It Is Used For


Simvastatin is a medicine used to lower levels of total cholesterol, “bad” cholesterol (LDL cholesterol), and fatty substances called triglycerides in the blood. In addition, Simvastatin raises levels of “good” cholesterol (HDL cholesterol). You should stay on a cholesterol-lowering diet while taking this medicine. Simvastatin is a member of the class of drugs called statins.


Simvastatin is used along with diet if you have:


  • a raised cholesterol level in your blood (primary hypercholesterolaemia) or elevated fat levels in your blood (mixed hyperlipidaemia)

  • a hereditary illness (homozygous familial hypercholesterolaemia) that increases the cholesterol level in your blood. You may also receive other treatments.

  • coronary heart disease (CHD) or are at high risk of CHD (because you have diabetes, history of stroke, or other blood vessel disease). Simvastatin may prolong your life by reducing the risk of heart disease problems, regardless of the amount of cholesterol in your blood.

In most people, there are no immediate symptoms of high cholesterol. Your doctor can measure your cholesterol with a simple blood test. Visit your doctor regularly, keep track of your cholesterol, and discuss your goals with your doctor.




Before You Take Simvastatin 80Mg



Do not take Simvastatin 80mg:


  • if you are allergic (hypersensitive) to simvastatin or to any of the other ingredients of the tablet

  • if you have liver problems or a continuous high level of certain liver enzymes (serum transaminases)

  • if you are pregnant or breast-feeding

  • if you are taking the following medicines (see also the section “Taking other medicines” below):

  • certain antifungals (ketoconazole or itraconazole)

  • certain medicines for the treatment of AIDS (HIV-protease inhibitors, such as indinavir, nelfinavir, ritonavir and saquinavir)

  • certain antibiotics (erythromycin, clarithromycin or telithromycin)

  • the antidepressant nefazodone



Take special care with Simvastatin 80mg:


  • Tell your doctor about all your medical conditions including allergies.

  • Tell your doctor if you drink large amounts of alcohol

  • Tell your doctor if you have ever had liver disease. Simvastatin may not be right for you.

  • Tell your doctor if you are due to have an operation. You may need to stop taking Simvastatin tablets for a short time.

  • Your doctor should do a blood test before you start taking Simvastatin. This is to check how well your liver is working.

  • Your doctor may also want you to have blood tests to check how well your liver is working after you start taking Simvastatin.


Contact your doctor immediately if you experience unexplained muscle pain, tenderness or weakness. This is because on rare occasions, muscle problems can be serious, including muscle breakdown resulting in kidney damage; and very rare deaths have occurred.


The risk of muscle breakdown is greater at higher doses of Simvastatin and is greater in certain patients. Tell your doctor if any of the following applies to you:


  • you consume large amounts of alcohol

  • kidney problems

  • thyroid problems

  • you are more than 70 years old

  • you have ever had muscle problems during treatment with cholesterol-lowering medicines called “statins” or fibrates

  • you or close family members have a hereditary muscle disorder.



Taking other medicines


It is particularly important to tell your doctor if you are taking any of the following drugs. Taking Simvastatin with any of these drugs can increase the risk of muscle problems (some of these have already been listed in the above section “Do not take Simvastatin 80mg:”)



Please note that the following statements may also apply to products you took some time ago or may take at some time in the future.


The risk of muscle problems can be greater if simvastatin is taken with the following medicines: (some of these have already been listed in the above section “Do not take the tablets”)


  • Fibrates (other cholesterol-lowering medicines, such as gemfibrozil, bezafibrate); the simvastatin dose should not exceed 10mg daily

  • Ciclosporin (drug used to suppress the immune system); the simvastatin dose should not exceed 10mg daily

  • Certain antifungals (such as itraconazole or ketoconazole)

  • The antibiotics erythromycin, clarithromycin and telithromycin

  • Certain medicines for the treatment of AIDS (HIV protease inhibitors, such as indinavir, nelfinavir, ritonavir and saquinavir)

  • Danazol (medicine used to treat endometriosis and breast cysts in women) the simvastatin dose should not exceed 10mg daily

  • The antidepressant nefazodone

  • Amiodarone, a medicine used for irregular heart beat; the simvastatin dose should not exceed 20mg daily

  • Verapamil and diltiazem (medicine used to treat high blood pressure, chest pain associated with heart disease, or other heart conditions); if you take verapamil, the dose of simvastatin should not exceed 20mg daily. If you take dilitazem, the dose of simvastatin should not exceed 40mg daily, unless your doctor considers that the clinical effects is likely to outweigh the increased risk of muscle problems

  • Fusidic acid as a tablet or infusion (a medicine used to treat bacterial infections)

As well as the medicines listed above, tell your doctor or pharmacist if you are taking or have recently taken any medicines, including those obtained without a prescription. In particular, tell your doctor if you are taking any of the following:


  • medicines to prevent blood clots, such as warfarin phenprocoumon or acenocoumarol (anticoagulants).

  • fenofibrate (another medicine for lowering cholesterol).

  • niacin (another medicine for lowering cholesterol).



Taking Simvastatin 80mg with food and drink


Grapefruit juice contains one or more components which may increase the amount of simvastatin in the blood. Therefore, you should not drink grapefruit juice as it could increase the risk of muscle damage.




Pregnancy and breast-feeding


Do not take simvastatin if you are pregnant, trying to become pregnant or suspect you may be pregnant, as the safety in pregnant women has not been established. If you become pregnant while using simvastatin, you must stop taking the tablets immediately and contact your doctor.


No data on the excretion of simvastatin in breast milk are available. Because many medicinal products are excreted in human milk and because of the potential for serious side effects, you must not breast-feed your infant while taking simvastatin.




Children


Simvastatin is not recommended for use in children.



Ask your doctor or pharmacist for advice before taking any medicine.




Driving and using machines


Simvastatin has no effect or only a negligible effect on the ability to drive or use machines. However, there have been rare cases of dizziness reported in patients taking simvastatin tablets (see section 4 “Possible side effects”). Do not drive vehicles or operate machines that require attention if you experience this side effect.




Important information about some of the ingredients of Simvastatin 80mg


Amongst other ingredients, Simvastatin 80mg tablets contain lactose monohydrate. If your doctor has told you that you cannot tolerate certain sugars, contact your doctor before taking this medicine.





How To Take Simvastatin 80Mg?


Always take your tablets exactly as your doctor has instructed you. You should check with your doctor or pharmacist if you are unsure.


Take the tablets either on an empty stomach or after a meal.


Before starting your treatment with Simvastatin 80mg you should be on a diet to lower your cholesterol and should keep on this diet while you are taking Simvastatin 80mg.


The usual dose is 5mg to 80mg simvastatin per day as a single dose in the evening. If needed, your doctor can increase the dose at intervals of at least 4 weeks to a maximum of 80mg per day as a single dose in the evening. The dose of 80mg is only recommended in patients with very high cholesterol levels and high-risk cardiovascular complications.


Your doctor will decide the appropriate dose for you and when you should take your tablets. This will depend on why you need to lower your cholesterol (see also section 1 “What Simvastatin 80mg is and what it is used for”):



Adults



  • To lower cholesterol and triglycerides in the blood (Hypercholesterolaemia), a usual starting dose is 10-20mg as a single dose in the evening. If a stronger effect is needed, the starting dose can be 20-40mg as a single dose in the evening. Your doctor can decide to increase the dose as mentioned above.


  • To lower inherited high levels of cholesterol in your blood (homozygous familial hypercholesterolemia), the recommended dose is 40mg as a single dose in the evening, or 80mg per day in 3 divided doses: 20mg in the morning, 20mg in the afternoon and 40mg in the evening.


  • To reduce the risk of coronary heart disease, the usual dose is 20-40mg as a single dose in the evening. Your doctor can decide to increase the dose as mentioned above.

If you have moderate kidney problems your dose will not have to be adjusted. If you have severe kidney problems your doctor may prescribe a lower dose, which will not be more than 10mg per day.


If your doctor has prescribed a bile acid sequestrant (another medicine for lowering cholesterol such as colestyramine) along with Simvastatin 80mg, you should take Simvastatin 80mg at least two hours before or four hours after taking the bile acid sequestrant.




Children and adolescents


Efficacy and safety of use in children have not been established.




Elderly


No dosage adjustment is necessary.




Duration of treatment:


You will have to take simvastatin over a long period of time. Your doctor will tell you how long you need to take simvastatin.



If you have the impression that the effect of simvastatin is too strong or too weak, talk to your doctor or pharmacist.




If you take more Simvastatin 80mg than you should


Although no specific information about simvastatin overdose is available, any medication taken in excess can have serious consequences. If you take too many tablets by mistake, contact a doctor or pharmacist immediately.




If you forget to take Simvastatin 80mg


If you realise you have forgotten to take a dose soon after its due time, take it as soon as possible. However, if it is almost time to take the next dose, omit the forgotten dose and take the next one when it is due. Ask your doctor or pharmacist in case of doubt.


Do not take a double dose to make up for a forgotten tablet.




If you stop taking Simvastatin 80mg


If you suddenly stop taking this medicine, your cholesterol may rise again. It is therefore important that you consult a doctor before stopping treatment. He/she can tell you if you can stop and the best way to do so.




If you have any further questions on the use of this product, ask your doctor or pharmacist.




Possible Side Effects


Like all medicines, Simvastatin 80mg can cause side effects, although not everybody will have them.


The following term is used to describe how often side effects have been reported:


Rare (occurring in 1 or more of 10,000 and less than 1 of 1000 patients treated)


The following rare serious side effects were reported.



If any of these serious side effects happen, stop taking the medicine and tell your doctor immediately or go to the emergency room at your nearest hospital.


  • muscle pain, tenderness, weakness, or cramps. On rare occasions, these muscle problems can be serious, including muscle breakdown resulting in kidney damage; and very rare deaths have occurred.

  • hypersensitivity (allergic) reactions including:

  • swelling of the face, tongue and throat which may cause difficulty in breathing

  • severe muscle pain usually in the shoulders and hips

  • rash with weakness of limbs and neck muscles

  • pain or inflammation of the joints

  • inflammation of the blood vessels

  • unusual bruising, skin eruptions and swelling, hives, skin sensitivity to the sun, fever, flushing

  • shortness of breath and feeling unwell

  • lupus-like disease picture (including rash, joint disorders, and effects on blood cells)

  • inflammation of the liver with yellowing of the skin and eyes, itching, dark-coloured urine or pale-coloured stool, liver failure (very rare)

  • inflammation of the pancreas often with severe abdominal pain.

The following side effects have also been reported rarely:


  • low red blood cell count (anaemia)

  • numbness or weakness of the arms and legs

  • headache, tingling sensation, dizziness

  • digestive disturbances (abdominal pain, constipation, flatulence, indigestion, diarrhoea, nausea, vomiting)

  • rash, itching, hair loss

  • weakness.


Laboratory values


Elevations in some laboratory blood tests of liver function and a muscle enzyme (creatine kinase) have been observed.


If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.




How To Store Simvastatin 80Mg


Keep out of the reach and sight of children.


Store the tablets in the original package in order to protect from light and moisture.


Do not store above 30°C.


Do not use the tablets after the ¨do not use after¨ or ¨expiry¨. date stated on the packaging. The first 2 digits denote the month, the last digits the year.


Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.




Further Information


What Simvastatin 80mg contains:


  • The active substance is: Simvastatin, 80mg per tablet

  • The other ingredients are:


Tablet core: Lactose monohydrate, cellulose microcrystalline (E460), pregelatinised maize starch, butylhydroxyanisole (E320), ascorbic acid (E300), citric acid (E330), colloidal anhydrous silica (E551), talc (E553b), magnesium stearate (E470b).
Film-coating: Hypromellose (E464), red iron oxide (E172), triethylcitrate (E1505), titanium dioxide (E171), talc (E553b), povidone K-30.



Product appearance and pack size


Simvastatin 80mg is a dark pink-coloured , oblong, film-coated tablet, scored on one side. The tablets can be divided into equal halves.


The tablets are packed in blisters in a carton box, containing 10, 20, 28, 30, 40, 50, 56, 60, 98 or 100 tablets. Not all pack sizes may be marketed.




Marketing Authorisation Holder and Manufacturer



Marketing Authorisation Holder



Actavis Group PTC ehf

Reykjavíkurvegur 76-78

220 Hafnarfjordur

Iceland



Manufacturers



Atlantic Pharma - Produções Farmacêuticas, S.A.

Rua da Tapada Grande No.2

2710-089 Sintra

Portugal




Actavis Nordic A/S

Ørnegårdsvej 16

DK-2820 Gentofte

Denmark




Distributor



Actavis

Barnstaple

EX32 8NS

UK




This leaflet was last revised in: October 2009



ATLPL000





Wednesday, March 14, 2012

Menorrhagia Medications


Definition of Menorrhagia: Menorrhagia is heavy or prolonged bleeding during your menstrual period.

Drugs associated with Menorrhagia

The following drugs and medications are in some way related to, or used in the treatment of Menorrhagia. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.





Drug List:

Monday, March 12, 2012

Crofab


Generic Name: antivenin (CROTALIDAE) POLYVALENT IMMUNE FAB (Intravenous route)


an-tye-VEN-in (kroe-TAL-i-dee) pol-ee-VAY-lent i-MUNE fab


Commonly used brand name(s)

In the U.S.


  • Crofab

Available Dosage Forms:


  • Powder for Solution

Therapeutic Class: Antivenom


Uses For Crofab


Pit viper antivenin is a medicine used to treat the bites of certain poisonous snakes called pit vipers (crotalids), which are native to North America. This particular pit viper antivenin is made from the blood of sheep and is used to treat the bites of the following types of pit viper: the Western Diamondback, Eastern Diamondback, and Mojave rattlesnakes, and the Copperhead snake or Water Moccasin.


Pit viper antivenin is to be used only by or under the supervision of a doctor.


Before Using Crofab


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Although there is no specific information comparing use of pit viper antivenin in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of pit viper antivenin in the elderly with use in other age groups.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Snake bite, previous— During previous treatment, your body may have developed antibodies (proteins produced by the immune system that help the body fight infection and are involved in allergic reactions), which may cause a serious reaction with current treatment

Proper Use of Crofab


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


Crofab Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Unexplained bleeding or bruising

Less common
  • Cough

  • difficulty in breathing

  • difficulty in swallowing

  • dizziness or lightheadedness

  • fast heartbeat

  • fever

  • hives or welts

  • itching of skin

  • joint pain

  • large, hive-like swellings on the eyelids, face, lips, mouth, and/or tongue

  • muscle pain

  • noisy breathing

  • redness of skin

  • shortness of breath

  • skin rash

  • wheezing

Check with your doctor as soon as possible if any of the following side effects occur:


Less common
  • Areas of pain, redness, and swelling

  • chest pain

  • chills

  • discharge from wound

  • pain, tenderness, and warmth at wound site

  • unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Nausea

Less common

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Crofab side effects (in more detail)


  • Back pain

  • generalized numbness, tingling, crawling, prickling, “pins and needles” feelings

  • hard bumps under the skin

  • loss of appetite

  • nervousness

  • numbness and tingling around the mouth

  • increased amount of phlegm


The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Crofab resources


  • Crofab Side Effects (in more detail)
  • Crofab Use in Pregnancy & Breastfeeding
  • Crofab Drug Interactions
  • Crofab Support Group
  • 0 Reviews for Crofab - Add your own review/rating


  • Antivenin (Crotalidae) Polyvalent Professional Patient Advice (Wolters Kluwer)

  • Antivenin (crotalidae) polyvalent



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Ultracaps


Generic Name: pancrelipase (Oral route)


AM-i-lase, LYE-pase, PROE-tee-ase


Commonly used brand name(s)

In the U.S.


  • Creon

  • Palcaps

  • Pancreaze

  • Pancrelipase

  • Pangestyme EC

  • Panocaps

  • Ultracaps

  • Zenpep

In Canada


  • Viokase

Available Dosage Forms:


  • Capsule, Delayed Release

  • Capsule

  • Tablet

  • Tablet, Chewable

  • Powder

Therapeutic Class: Enzyme Replacement


Pharmacologic Class: Enzyme


Uses For Ultracaps


Pancrelipase is used to help improve food digestion in certain conditions (e.g., cystic fibrosis) where the pancreas is not working properly.


Pancrelipase contains the enzymes needed for the digestion of proteins, starches, and fats.


This medicine is available only with your doctor's prescription.


Before Using Ultracaps


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of pancrelipase in children.


Geriatric


No information is available on the relationship of age to the effects of pancrelipase in geriatric patients.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Allergy to pork products—Use with caution. Pancrelipase contains pork proteins.

  • Gout or

  • Hyperuricemia (high uric acid in the blood) or

  • Hyperuricosuria (high uric acid in the urine) or

  • Intestinal (bowel) blockage, history of or

  • Kidney disease or

  • Pancreatitis (inflammation of the pancreas)—Use with caution. May make these conditions worse.

Proper Use of pancrelipase

This section provides information on the proper use of a number of products that contain pancrelipase. It may not be specific to Ultracaps. Please read with care.


Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.


This medicine should come with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.


Take this medicine with meals or snacks and enough liquid to swallow it completely, unless otherwise directed by your doctor.


When prescribing this medicine for your condition, your doctor may also prescribe a personal diet for you. Follow the special diet carefully. This is necessary for the medicine to work properly. It is also important to drink plenty of water while you are on this medicine.


For patients taking the tablets:


  • Swallow the tablets quickly with some liquid, without chewing, to avoid mouth irritation.

For patients taking the delayed-release capsules:


  • Swallow the capsule whole.

  • Do not crush, break, or chew before swallowing. Do not hold the capsule in your mouth.

  • When given to children, the capsule may be opened and sprinkled on a small amount of soft food that can be swallowed without chewing, such as applesauce, gelatin, pureed bananas, or pears. This mixture must be swallowed immediately and followed with a glass of water or juice. This will ensure complete swallowing of the contents of the capsule and avoid mouth irritation.

  • When given to infants, the contents of the capsule may be put directly into the infant's mouth or mixed with a small amount of applesauce, pureed bananas, or pears, and given before each feeding.

  • Do not mix the contents of the capsule with alkaline foods, such as milk, breast milk, formula, or ice cream. This could reduce the effect of the medicine.

Do not change brands or dosage forms of pancrelipase without first checking with your doctor. Different products may not work in the same way. If you refill your medicine and it looks different, check with your pharmacist.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • To help digestion:
    • For oral dosage form (capsules):
      • Older adults, adults, and teenagers—One to three capsules before or with meals and snacks. Your doctor may adjust your dose if needed.

      • Children—The contents of one to three capsules sprinkled on food at each meal. Your doctor may adjust your dose if needed.


    • For oral dosage form (delayed-release capsules):
      • Older adults, adults, teenagers, and children older than 4 years of age—Dose is based on body weight and must be determined by your doctor. The starting dose is 500 lipase units per kilogram (kg) of body weight per meal. However, the dose is usually not more than 2500 lipase units per kg of body weight per meal (or less than or equal to 10,000 lipase units per kg of body weight per day), or less than 4000 lipase units per gram (g) of fat ingested per day.

      • Children older than 12 months and younger than 4 years of age—Dose is based on body weight and must be determined by your doctor. The starting dose is 1000 lipase units per kilogram (kg) of body weight per meal. However, the dose is usually not more than 2500 lipase units per kg of body weight per meal (or less than or equal to 10,000 lipase units per kg of body weight per day), or less than 4000 lipase units per gram (g) of fat ingested per day.

      • Infants younger than 12 months—
        • Creon®: 3000 lipase units per 120 milliliters (mL) of infant formula or per breastfeeding.

        • Zenpep®: 3000 lipase units per 120 mL of infant formula or per breastfeeding.

        • Pancreaze™: 2000 to 4000 lipase units per 120 mL of infant formula or per breastfeeding.



    • For oral dosage form (powder):
      • Older adults, adults, and teenagers—1/4 teaspoonful (0.7 gram) with meals and snacks. Your doctor may adjust your dose if needed.

      • Children—1/4 teaspoonful with meals. Your doctor may adjust your dose if needed.


    • For oral dosage form (tablets):
      • Older adults, adults, and teenagers—One to three tablets before or with meals and snacks. Your doctor may adjust your dose if needed.

      • Children—One to two tablets with meals.



Missed Dose


If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


You may store Creon® capsules at room temperature for 30 days. Throw away any unused medicine after 30 days.


Store the delayed-release capsules in a tightly-closed container to protect them from moisture. Putting desiccant pouches in the container may also help to keep the capsules from getting moist.


Precautions While Using Ultracaps


It is very important that your doctor check the progress of you or your child at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you or your child should continue to take it.


For patients taking the capsules containing the powder:


  • If the capsules are opened to mix with food, be careful not to breathe in the powder. To do so may cause harmful effects such as stuffy nose, shortness of breath, troubled breathing, wheezing, or tightness in the chest.

For patients taking the powder form of this medicine:


  • Avoid breathing in the powder. To do so may cause harmful effects such as stuffy nose, shortness of breath, troubled breathing, wheezing, or tightness in the chest.

Check with your doctor right away if you or your child have unusual or severe abdominal or stomach pain, trouble passing stool, nausea, or vomiting. These may be symptoms of a rare but serious bowel disorder called fibrosing colonopathy.


This medicine is made from the pancreas of pigs. The risk of getting a virus from medicines made of pig organs has been greatly reduced in recent years. This is the result of required testing for certain viruses, and testing during manufacture of these medicines. Although the risk of transmitting certain viruses to people who will use the medicine is low, talk with your doctor if you or your child have concerns.


This medicine may cause a serious type of allergic reaction, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have itching; hives; hoarseness; trouble with breathing; trouble with swallowing; or any swelling of your hands, face, or mouth while you or your child are using this medicine.


Ultracaps Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Rare
  • Skin rash or hives

With high doses
  • Bowel blockage

  • diarrhea

  • nausea

  • stomach cramps or pain

With very high doses
  • Blood in the urine

  • joint pain

  • swelling of the feet or lower legs

With powder dosage form or powder from opened capsules - if breathed in
  • Shortness of breath

  • stuffy nose

  • tightness in the chest

  • troubled breathing

  • wheezing

With tablets - if held in mouth
  • Irritation of the mouth

Incidence not known
  • Cough

  • difficulty with breathing

  • difficulty with swallowing

  • dizziness

  • fast heartbeat

  • itching

  • noisy breathing

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • redness of the skin

  • severe stomach pain

  • unusual tiredness or weakness

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Blurred vision

  • dry mouth

  • flushed, dry skin

  • fruit-like breath odor

  • headache

  • increased hunger

  • increased thirst

  • increased urination

  • sweating

  • unexplained weight loss

  • vomiting

Less common
  • Abnormal feces

  • anxiety

  • bloated

  • chills

  • cold sweats

  • coma

  • confusion

  • cool, pale skin

  • depression

  • excess air or gas in the stomach or intestines

  • fever

  • frequent bowel movements

  • full feeling

  • muscle aches

  • nightmares

  • passing gas

  • runny nose

  • seizures

  • shakiness

  • slurred speech

  • sore throat

Incidence not known
  • Difficulty having a bowel movement (stool)

  • difficulty with moving

  • muscle aching or cramping

  • muscle pains or stiffness

  • muscle spasm

  • swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Ultracaps side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Ultracaps resources


  • Ultracaps Side Effects (in more detail)
  • Ultracaps Use in Pregnancy & Breastfeeding
  • Drug Images
  • Ultracaps Drug Interactions
  • Ultracaps Support Group
  • 10 Reviews for Ultracaps - Add your own review/rating


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Sunday, March 11, 2012

Uramaxin GT Solution


Pronunciation: ue-REE-a
Generic Name: Urea
Brand Name: Uramaxin GT


Uramaxin GT Solution is used for:

Promoting the healing of certain conditions of the fingernails and toenails (eg, hyperkeratotic conditions). It may also be used to treat certain other skin conditions (eg, corns; calluses; rough, dry skin) as determined by your doctor.


Uramaxin GT Solution is a debriding agent. It works by helping the breakdown of dead skin and pus, which helps to soften, loosen, and shed hard, scaly skin and nails.


Do NOT use Uramaxin GT Solution if:


  • you are allergic to any ingredient in Uramaxin GT Solution

Contact your doctor or health care provider right away if any of these apply to you.



Before using Uramaxin GT Solution:


Some medical conditions may interact with Uramaxin GT Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Uramaxin GT Solution. Because little, if any, of Uramaxin GT Solution is absorbed into the blood, the risk of it interacting with another medicine is low.


Ask your health care provider if Uramaxin GT Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Uramaxin GT Solution:


Use Uramaxin GT Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Uramaxin GT Solution is for external use only.

  • Apply a thin layer of Uramaxin GT Solution to the affected area. After application, wipe the tip to remove excess medicine and replace the cap.

  • If you miss a dose of Uramaxin GT Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Uramaxin GT Solution.



Important safety information:


  • Uramaxin GT Solution is for external use only. Do not get it in your eyes, nose, mouth, or lips or on your genitals. If you get it in any of these areas, rinse right away with cool water.

  • PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Uramaxin GT Solution while you are pregnant. It is not known if Uramaxin GT Solution is found in breast milk after topical use. If you are or will be breast-feeding while you use Uramaxin GT Solution, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Uramaxin GT Solution:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Mild skin irritation; temporary burning, stinging, or itching.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); redness; severe or persistent burning or irritation.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Uramaxin GT side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Uramaxin GT Solution:

Store Uramaxin GT Solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Uramaxin GT Solution out of the reach of children and away from pets.


General information:


  • If you have any questions about Uramaxin GT Solution, please talk with your doctor, pharmacist, or other health care provider.

  • Uramaxin GT Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Uramaxin GT Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

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  • Uramaxin GT Side Effects (in more detail)
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